Postdoc Fellow in Clinical & Translational Medicine Informatics

About the LCSB

The University of Luxembourg is an international research university with a distinctly multilingual and interdisciplinary character.

The Luxembourg Centre for Systems Biomedicine (LCSB) is an interdisciplinary research centre of the University of Luxembourg.
We conduct fundamental and translational research in the field of Systems Biology and Biomedicine - in the lab, in the clinic and in silico. We focus on neurodegenerative processes and are especially interested in Alzheimer's and Parkinson's disease and their contributing factors. The LCSB recruits talented scientists from various disciplines: computer scientists, mathematicians, biologists, chemists, engineers, physicists and clinicians from more than 50 countries currently work at the LCSB. We excel because we are truly interdisciplinary, and together we contribute to science and society.

Successful candidate will join the Bioinformatics Core, led by Prof. Reinhard Schneider, which focuses on managing and analysing complex biomedical and clinical data. We are internationally recognized for our GDPR compliant data hosting solutions and data management systems. We develop innovative methodologies for data mining, federated data analysis, and data FAIRification. We strongly advocate following responsible and reproducible research (R3) principles and best practices in software development. For more information, please visit our website.

We are looking for a Postdoc to analyse high throughput single and bulk cell RNA sequencing datasets, spatial transcriptomics and multi-omics (metabolomics and proteomics) datasets. The successful candidate will be involved in translational medicine projects and will explore and analyse large and heterogenous datasets in human diseases, primarily in immunological and neurodegenerative disorders. The successful candidate will also take an active role on project activities and effectively disseminating findings to the project members and the scientific community through project meeting, conferences and publications.

Your role

• Coordinate the analysis of multiomics data sets including next-generation sequencing, single cell/nuclear transcriptomics, bulk RNA sequencing, spatial transcriptomics, metabolomics and proteomics datasets
• Coordinate pre-clinical and clinical data capture, curation, harmonization, integration and analysis
• Perform integration and analysis of project data with data from public repositories and literature
• Work closely with other team members on the design and implementation of bioinformatics workflows and visualization tools
• Take an active role on project activities, working closely with a multidisciplinary team to meet project goals effectively
• Disseminate the ongoing work and research findings with the project members, the scientific community and other stakeholders through project meetings, conferences and publications

For further information, please contact Dr. Venkata SATAGOPAM ().

Your profile

• A PhD in computational biology, bioinformatics or related fields, with an interest in biomedical informatics and translational medicine
• Prior experience in analysis of bulk, single-cell/nuclear, spatial transcriptomics as well as multi-omics data is necessary
• Demonstrated expertise in R programming with a strong command of bioinformatics workflows, including data manipulation, statistical analysis, and visualization using relevant packages from Bioconductor including DESeq2, limma, BioMart, Seurat, gViz, and edgeR
• Experience in developing interactive web applications and data visualizations with R Shiny, Plotly, ggplot2, and Seaborn or similar dataviz libraries
• Strong verbal and written communication skills, the ability to clearly articulate scientific and technical needs, and a demonstrated capacity for collaboration in a team-oriented research environment
• Proficiency in Python with data science/machine learning libraries is considered an advantage
• Familiarity on working on High-Performance Computing (HPC) environment and with UNIX systems including SHELL or AWK scripting is an advantage
• Prior experience dealing with pre-clinical, clinical, molecular and imaging data integration, NoSQL/ graph database technologies and research experience in immunological diseases is considered an advantage

We offer

• Multilingual and international character. Modern institution with a personal atmosphere. Staff coming from 90 countries. Member of the "University of the Greater Region" (UniGR)
• A modern and dynamic university. High-quality equipment. Close ties to the business world and to the Luxembourg labour market. A unique urban site with excellent infrastructure
• A partner for society and industry. Cooperation with European institutions, innovative companies, the Financial Centre and with numerous non-academic partners such as ministries, local governments, associations, NGOs …

How to apply

Applications should include:

• A detailed curriculum vitae (CV) including a list of publications and projects
• A cover letter describing experience and future interests
• Contact information and recommendation letters from at least three referees

Early application is highly encouraged, as the applications will be processed upon reception. To ensure full consideration, candidates should apply by 31.01.2025 ONLINE formally through the HR system. Applications by Email will not be considered.

All qualified individuals are encouraged to apply. In line with our values, the University of Luxembourg promotes an inclusive culture. We encourage applications from individuals of all backgrounds and are dedicated to upholding equality and respect for our employees and students.

General information:

• Contract Type: Fixed Term Contract 36 Month (extension possible)
• Work Hours: Full Time 40.0 Hours per Week
• Location: Campus Belval
• Internal Title: Postdoctoral researcher
• Job Reference: UOL06999

The yearly gross salary for every Postdoctoral Researcher at the UL is EUR 83099 (full time).