Postdoctoral Researcher in Glial Biology and Epigenomics

About us

The University of Luxembourg is an international research university with a distinctly multilingual and interdisciplinary character.

The Faculty of Science, Technology and Medicine (FSTM) at the University of Luxembourg contributes multidisciplinary expertise in the fields of Mathematics, Physics, Engineering, Computer Science, Life Sciences and Medicine.
Through its dual mission of teaching and research, the FSTM seeks to generate and disseminate knowledge and train new generations of responsible citizens in order to better understand, explain and advance society and the environment we live in.

Your role

• Design and perform single-cell and bulk level multiomic experiments linking gene expression with chromatin profiling using glial cells from different mouse brain regions
• Analyse and integrate single-cell transcriptomic and epigenomic data with complementary datasets generated by the collaborating group to identify glial subpopulations, regulatory elements and gene regulatory networks
• Establish and work with primary mouse astrocyte and oligodendroglial cultures to validate candidate regulators using gene overexpression, RNA interference and/or CRISPR-based epigenome editing
• Test how regional identity and sex hormones influence glial functions, oxidative stress vulnerability and metabolic phenotypes, in coordination with the project's collaborators
• Take responsibility for the Luxembourg research activities, coordinate closely with the Saarland team, and document experiments and analyses reproducibly
• Prepare manuscripts, present findings at scientific meetings, and contribute to the group's teaching and student mentoring activities

Your profile

• A PhD in molecular biology, biochemistry, neuroscience, epigenetics, bioinformatics or a closely related discipline
• Demonstrated expertise in experimental molecular biology and mammalian cell culture. Experience with primary glial cells, mouse models, or other relevant neural cell models is particularly welcome
• A strong interest in gene regulation, epigenetics and glial biology, and a willingness to develop computational skills and connect molecular datasets with functional experiments
• Experience in single-cell sequencing data analysis or multiomic data integration is desirable. Experience with chromatin profiling, RNA interference or CRISPR-based perturbation will also be an advantage
• A record of communicating research through scientific publications and/or presentations
• Excellent command of English

We offer

• A modern, dynamic university with a personal and inclusive atmosphere. Multilingual and international character. Staff coming from more than 90 countries. Member of The Guild of European Research Intensive Universities
• An exceptional research environment, supported by skilled staff and high-quality equipment. Strong links to professional sectors and the Luxembourg labour market. A unique urban campus with excellent infrastructure
• A partner for society and industry. Cooperation with European institutions, innovative companies, the Financial Centre and a wide range of non-academic partners including ministries, local governments, associations, and NGOs

How to apply

Applications should include:

Early application is highly encouraged, as the applications will be processed upon reception. Please apply ONLINE formally through the HR system. Applications by Email will not be considered.

All qualified individuals are encouraged to apply. In line with our values, the University of Luxembourg promotes an inclusive culture. We encourage applications from individuals of all backgrounds and are dedicated to upholding equality and respect for our employees and students.

General information:

• Contract Type: Fixed Term Contract 24 Month
• Work Hours: Full Time 40.0 Hours per Week
• Location: Belval Campus
• Internal Title: Postdoctoral researcher
• Job Reference: UOL08537

The yearly gross salary for every Postdoctoral Researcher at the UL is EUR 87306 (full time).